데이터베이스연구회

□ 사례 19 - 비만 억제 또는 치료용 조성물 - ▶분야 : 화학(정밀화학) ▶기술내용 : 진세노사이드(ginsenoside)-Rf 또는 화합물 K(Compound K)를 유효성분으로 포함하는 비만억제 또는 치료용 조성물에 관한 것으로, TAG 함량을 감소시키고 전구지방세포의 지방세포로의 분화과정을 조절하여 지질량을 감소시키며, 지방세포의 분화과정 중 에너지 소비를 증진시키는 유전자들의 발현을 증가시켜 항-비만 효능 개선 ▶TITLE ○작성내용 : COMPOSITION FOR PREVENTING AND TREATING OBESITY COMPRISING GINSENOSIDE-RF OR COMPOUND K SHOWING EXCELLENT STABILITY ON HUMAN BODY AS EFFECTIVE INGREDIENT ○수정내용 : COMPOSITION FOR PREVENTING AND TREATING OBESITY COMPRISING GINSENOSIDE-Rf OR COMPOUND K SHOWING EXCELLENT STABILITY ON HUMAN BODY AS EFFECTIVE INGREDIENT ·GINSENOSIDE-RF -> GINSENOSIDE-Rf ▶PURPOSE ○작성내용 : A composition comprising ginsenoside-Rf or a compound K is provided to decrease the TAG content of fat cells and control the differentiation of pre-fat cells into the fat cells in order to decrease the lipid amount ad increase the expression of genes promoting energy consumption during the differentiation step of the fat cells, thereby ultimately showing anti-obesity capability. ○수정내용 : A composition comprising ginsenoside-Rf or a compound K is provided to decrease the TAG content of fat cells and control the differentiation of pre-fat cells into the fat cells in order to decrease the lipid amount and increase the expression of genes promoting energy consumption during the differentiation step of the fat cells, thereby ultimately showing anti-obesity capability. ·용어: photo-matrix solution -> black matrix solution, blading electrode compositions -> blading conductive electrode materials (도전성 적극 구성물) ▶CONSTITUTION ○작성내용 : The composition for preventing and treating obesity comprises ginsenoside-Rf or a compound K as an effective ingredient. The composition is a food composition or a pharmaceutical composition. ○수정내용 : The composition for preventing and treating obesity comprises ginsenoside-Rf or a compound K as an effective ingredient. The ginsenoside-Rf is a saponin ingredient of ginseng or red ginseng and represented by the formula(1), wherein R1 is H, R2 is –O-Glc-Glc, and R3 is H, and the compound K is internal metabolite and represented by the formula(1), wherein R1 is OH, R2 is H, and R3 is Glc. The composition is a food composition or a pharmaceutical composition. ·The ginsenoside-Rf is a saponin ingredient of ginseng or red ginseng and represented by the formula(1), wherein R1 is H, R2 is –O-Glc-Glc, and R3 is H, and the compound K is internal metabolite and represented by the formula(1), wherein R1 is OH, R2 is H, and R3 is Glc. <=주요 유효성분인 ginsenoside-Rf 와 compound K에 대한 특징 설명이 미흡하여 추가